ABSTRACT
BACKGROUND: We investigated a group of patients with chronic renal failure to evaluate the prevalence and the risk factor related to sleep disturbance. We also studied to explore relationship between sleep disturbance and renal replacement therapy of chronic renal failure such as hemodialysis (HD), peritoneal dialysis (PD) and renal transplantation (RT). METHODS: The patients with 43 HD patients, 52 PD patients, and 32 RT patients completed a self- administered questionnaire package, which included Weekly Sleep Questionnaire (WSQ) and Beck's Depression Inventory (BDI). RESULTS: About 75% of chronic renal failure patients have sleep disturbance. There was difference of morning dissatisfaction feeling item score between HD and RT (pRT) groups and of daytime sedation item score among PD, HD and RT (pRT, PDRT) groups. The BDI (beta= 0.546) and the serum creatinine (beta=0.221) were significantly positive correlated with WSQ total score, but other factors (modalities of renal replacement therapy, duration of illness, duration of dialysis, Bood urea nitrogen, hematocrit, Body mass index) were not correlated with WSQ total score. CONCLUSION: Sleep disturbance is common in chronic renal failure patients. There was significant difference of daytime sleep disturbance among renal replacement therapy groups. It was caused by difference of emotional state and physical states.